Generic Name
Milbemycin Oxime (mil’-beh-my’-sin ox’-eem) and
Lufenuron (lew-fen’-your-on)

Brand Name(s)
Sentinel (Novartis)

How this medicine should be used
Milbemycin oxime with Lufenuron is indicated for use in dogs and puppies four weeks of age and older, and two pounds body weight or greater. The usual dose of milbemycin oxime with Lufenuron for dogs 2-10 pounds is 2.3mg/46mg, 11-25 pounds is 5.75mg/115mg, 26-50 pounds is 11.5mg/230mg and 51-100 pounds is 23mg/460mg given once a month year round. An alternate treatment is to give this medication once a month during the mosquito season and also one month after the season ends.

What are the side effects
Side effects of Milbemycin oxime with Lufenuron are rare although some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, seizures, convulsions, hypersali-vation and weakness.

What special precautions are there
This medication should not be used in animals allergic to it. The pet should be tested for heartworm disease before starting this medication. If the pet has been off heartworm preventative for 6 months or more, retest in 6 months since microfilaria, that take 6 months to mature, will cause a positive test result. Because humans can contract hookworm and roundworm from animals it is important to maintain good personal hygiene. It is also important to eliminate fleas on the pet and in the household and to not feed the pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended.

In the event of overdose
Contact your veterinarian or veterinary emergency room.

How should I store this medication
Keep this medication in the original box. Do not remove the tablet from the foil wrap until ready to give the medication. Keep this medication out of the reach of children and pets.

 

Sentinel®